Unlike its California brethren, however, Columbus' Budweiser plant opened up with some brewing competition in the area, mainly in the form of August Wagner. At that time, Wagner, which launched in 1905 as Gambrinus Brewing and Bottling, held the unique distinction as the only brewery in the city established prior to Prohibition to actually survive and function as a brewery after the law's repeal.
Columbus Brewing, started up by current Temperance Row Brewing brewer Scott Francis, set up shop in 1988.
Nowadays, Columbus' craft brewery roll call numbers closer to forty, but even combined they almost certainly don't compare volume-wise to the local Budweiser plant's roughly 10 million barrels of production in 2015, according to this Dayton Daily News article. Perhaps it's only appropriate that the Columbus craft brewery within closest stone's throw of the city's "Big Beer" representative comes at the term from a completely different direction.